PumasCP Learning Path

Module 1: Overview to PumasCP

Studies

• Create a study (Video)
• Import a study (Video)
• Delete (bulk) a study (Video)

PumasCP support

• Help via widget (Video)
• Documentation links (Video)
• Extending session (Video)

Study dashboard

• Datasets, tasks and reports (Video)
• Tasks (Video)
• Reports (Video)
• Creating a template for a study (Video)

Module 2: Study Dashboard

Dataset

• Uploading different file formats (Video)
• Using example datasets (Video)
• Edit uploaded file (Video)
• Transform - Datawrangling (Video)
• Duplicate (Video)

Module 3: Data Transformation

Core transformations

• Select columns (Video)
• Rename (Video)
• Relocate (Video)
• Convert (Video)
• Filter rows (Video)
• Order by (Video)
• Group by (Video)
• Ungroup (Video)
• Derive (Video)
• Define Route (Video)
• Convert Unit (Video)
• Infer units (Video)
• Sample rows (Video)
• Slice Rows (Video)
• Count (Video)

Reshape

• Fold (Video)
• Pivot (Video)

Clean

• Remove duplicates (Video)
• Impute (Video)

Set

• Concat (Video)
• Union (Video)
• Intersect (Video)
• Except (Video)

Join

• Inner, outer, left, right, cross, semi and anti join (Video)

Metadata

• Label and Notes (Video)

Module 4: Non-compartmental analysis - Workflow

Tasks

• Task Overview (Video)
• Create a task (Video)
• Choosing an analysis template (Video)
• Duplicate a task (Video)
• Create a template task (Video)

Mapping

• Automapping of columns (Video)
• Mapping columns for plasma and urine PK data (Video)
• Grouping variables (Video)
• Enabling Sparse analysis mode (Video)
• Specifying LLOQ and BLQ (Video)
• Error at Step 3 NCA (Video)
• Correct mapping (Video)

Subject Data Review

• Study data summary (Video)
• Listing of concentrations table (Video)
• Observations vs time plots (Video)
• Summary observations vs time plots (Video)
• Subject fit plots (Video)

Figures

• Formatting default figures (Video)
• Adding new figures (Video)

Tables

• Formatting default tables (Video)
• Adding new tables (Video)

NCA Preferences

• Regression Method (Video)
• Threshold (Video)
• Rules - Overview (Video)
• BLQ (Video)
• R2 (Video)
• AUC % Extrapolated (Video)

Custom parameters

• Parameters to Summarize (Video)
• Partial AUC calculation - Part 1 (Video)
• Partial AUC calculation - Part 2 (Video)

Explore Subjects

• Navigation of groups (Video)
• Linear/Log (Video)
• R2 Flag (Video)
• Navigation of subjects (Video)
• Exclude subjects (Video)
• Exclude data points (Video)
• Edit start and end for terminal points (Video)
• Apply notes (Video)

Review NCA Results

• Raw results vs Transformed results (Video)
• Ratio table and Summary table (Video)
• NCA Parameter Listing table (Video)
• Figures (Video)

Generating a report

• Create a report by choosing task(s) (Video)
• Selecting results to be reported (Video)
• Metadata for report (Video)
• View/Download/Edit/Remove a report (Video)

Module 5: Non-compartmental analysis - Workflow for different study designs

Study design

• Drug-Drug Interaction Study NCA (Video)
• Multiple dose and multiple ascending dose (MAD) study with intra-cohort dose escalation (Video)
• Non-replicated crossover study NCA (Video)
• Food effect Study NCA (Video)